If blood gets in the sample or if there is an infection present, the pH of the vaginal fluid may be higher than normal. This test, however, can produce false positives. A blue strip means it’s more likely the membranes have ruptured. The strips will turn blue if the pH is greater than 6.0. The strips change color depending on the pH of the fluid. This test involves putting a drop of fluid obtained from the vagina onto paper strips containing Nitrazine dye. Therefore, if the membranes have ruptured, the pH of the sample of vaginal fluid will be higher than normal. Amniotic fluid has a higher pH of 7.1 to 7.3. Normal vaginal pH is between 4.5 and 6.0. This test involves testing the pH of a sample of vaginal fluid. This allows them to examine the inside of the vagina and to collect fluid directly from the vagina. They will insert the speculum into the vagina and gently spread apart the vaginal walls. Your health care provider will collect some fluid from the vagina using a medical tool called a speculum in order to do most of these tests. Since the fluids might be contaminated with blood or other secretions, these tests look for substances or certain characteristics that are normally only found in amniotic fluid. Tests for PROM involve analyzing vaginal secretions to determine if amniotic fluid is present. They will then order tests to help confirm PROM or PPROM. Your health care provider will examine you and observe the fluid coming from the vagina. These tiny ruptures cannot be detected with traditional methods, but are clinically relevant as they can induce delivery, cause infections, and threaten the health of both mother and child.īecause Actim PROM is specific to amniotic fluid IGFBP-1, tests can be completed even in the presence of blood and other bodily fluids, infections, and medical products.If you suspect that your water has broken and there is fluid leaking from the vagina, your health care provider will need to confirm that the membranes have actually ruptured. Thanks to its high sensitivity, Actim PROM detects even low concentrations of IGFBP-1 caused by micro-ruptures in the fetal membrane. Actim PROM detects IGFBP-1 in vaginal swab samples and helps to identify membrane ruptures. Amniotic fluid is normally not found in the vagina, but when fetal membranes rupture, amniotic fluid leaks into the vagina and the IGFBP-1 concentration quickly rises and remains high until delivery. How Actim prom works Actim ® PROM and Vaginal IGFBP-1Īctim PROM rapid test is based on highly specific monoclonal antibodies that bind to the insulin-like growth factor binding protein-1 (IGFBP-1) present in amniotic fluid in high amounts. Actim PROM is available in multiple package sizes.The test kit contains all the materials required to perform the test and it can be stored at room temperature.The test results are not affected by blood, intercourse, semen, urine, vaginal medications, bathing products, or infections.Actim PROM is an easy-to-use one-step dipstick test that gives test results at the bedside in just 5 minutes, with sampling completed in seconds – with or without speculum.The test can be performed at any gestational age.Actim PROM is a rapid test that reliably detects PROM, even before any clinically visible signs can be detected.
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